Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564320 | 0.88 | CNR2 (0.39) | CNR2BRD4CYP11B2BAZ2ABRAF | |
| SCHEMBL2571322 | 0.87 | CNR2 (0.41) | CNR2BRD4PDE10ACNR1 | |
| SCHEMBL12393459 | 0.86 | CNR2 (0.37) | CNR2BRD4BAZ2ABRAFCNR1 | |
| SCHEMBL2573492 | 0.86 | CYP11B2 (0.42) | CNR2BRD4CYP11B2BAZ2ABRAF | |
| SCHEMBL2571829 | 0.83 | CNR2 (0.39) | CNR2BRD4BAZ2APDE10ACNR1 | |
| SCHEMBL2572048 | 0.81 | NR5A2 (0.42) | CNR2PDE10ACNR1 | |
| SCHEMBL2570363 | 0.81 | CNR2 (0.39) | CNR2BRD4BAZ2APDE10ACNR1 | |
| Hydrochloric Acid SCHEMBL2566184 | 0.80 | CNR2 (0.42) | CNR2BRD4PDE10ACNR1 | |
| SCHEMBL2571598 | 0.80 | RIPK3 (0.45) | CNR2PDE10A | |
| SCHEMBL2571955 | 0.80 | KDM2B (0.50) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289502-A1 | IMIDAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-8273738-B2 | Imidazole derivatives | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| EP-2090570-B1 | IMIDAZOLE DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289502-A1 | IMIDAZOLE DERIVATIVES | CNR1, CNR2, ARRB1 | CNR2 2/4885BRD4 72/4885CYP11B2 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.