Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 7/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696802 | 0.95 | GNAO1 (0.35) | GNAO1GNAI3GNAI1LMNANPC1 | |
| SCHEMBL23696383 | 0.92 | GNAO1 (0.38) | GNAO1GNAI3GNAI1NPC1BCHE | |
| SCHEMBL22856209 | 0.92 | GNAO1 (0.45) | GNAO1GNAI3GNAI1NPC1CARM1 | |
| SCHEMBL23568457 | 0.92 | GNAO1 (0.41) | GNAO1GNAI3GNAI1NPC1BCHE | |
| SCHEMBL25469357 | 0.90 | GNAO1 (0.44) | GNAO1GNAI3GNAI1NPC1BCHE | |
| SCHEMBL22794642 | 0.90 | NPC1 (0.41) | GNAO1GNAI3GNAI1NPC1BCHE | |
| SCHEMBL23807056 | 0.90 | GNAO1 (0.36) | GNAO1GNAI3GNAI1NPC1BCHE | |
| SCHEMBL25123296 | 0.90 | GNAO1 (0.36) | GNAO1GNAI3GNAI1NPC1BCHE | |
| SCHEMBL25480405 | 0.87 | GNAO1 (0.40) | GNAO1GNAI3GNAI1 | |
| SCHEMBL25928339 | 0.87 | GNAO1 (0.40) | GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | GNAO1 2977/4885GNAI3 1664/4885GNAI1 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.