Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665143 | 0.74 | FFAR3 (0.33) | POLBAPEX1TDP1 | |
| SCHEMBL638769 | 0.70 | POLB (0.46) | POLBAPEX1TDP1 | |
| SCHEMBL27514165 | 0.70 | — | — | |
| SCHEMBL12492015 | 0.66 | POLB (0.42) | POLBAPEX1TDP1 | |
| SCHEMBL12491887 | 0.66 | POLB (0.42) | POLBAPEX1TDP1 | |
| SCHEMBL12492014 | 0.66 | POLB (0.42) | POLBAPEX1TDP1 | |
| SCHEMBL17827137 | 0.62 | — | — | |
| SCHEMBL1627758 | 0.62 | — | — | |
| SCHEMBL386786 | 0.61 | — | — | |
| SCHEMBL7340145 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382200-A1 | COMPETITIVE INHIBITORS OF TYPE II DEHYDROQUINASE ENZYME | Universidade De Santiago De Compostela (ES) | 2011-11-02 | — | — | EP | claimed |
| WO-2010072813-A1 | COMPETITIVE INHIBITORS OF TYPE II DEHYDROQUINASE ENZYME | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2010-07-01 | — | — | WO | claimed |