SCHEMBL2570822

SCHEMBL2570822

CC(C)(C)c1ccccc1OP(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 1/20 0.41
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 3/20 0.39
GAA P10253 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
RIPK1 Q13546 1/20 0.36
NISCH Q9Y2I1 1/20 0.35
RBP4 P02753 2/20 0.35
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381269 1.00 TDP1 (0.41) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL30008905 1.00 TDP1 (0.41) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL29405808 0.90 MAPT (0.44) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL380498 0.90 MAPT (0.44) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL28552345 0.89 TDP1 (0.40) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL29133656 0.86 TDP1 (0.35) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL9240035 0.86 TDP1 (0.35) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL9491543 0.82 TDP1 (0.43) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL1160297 0.82 MEN1 (0.34) TDP1MAPTTP53ALDH1A1GAA
SCHEMBL9240542 0.82 APEX1 (0.38) TDP1MAPTALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951289-B2 Refrigeration oil PATECH FINE CHEMICALS CO., LTD. (TW) 2018-04-24 US disclosed
US-20160281017-A1 NOVEL REFRIGERATION OIL PATECH FINE CHEMICALS CO., LTD. (TW) 2016-09-29 US disclosed
EP-1486536-B2 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-10-10 EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
US-7498375-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2009-03-03 US disclosed
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 US disclosed
US-20050004292-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2005-01-06 US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1486536-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-12-15 EP disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed