SCHEMBL381269

SCHEMBL381269

CC(C)(C)c1ccccc1OP(Oc1ccccc1)Oc1ccccc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 1/20 0.41
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 3/20 0.39
GAA P10253 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
RIPK1 Q13546 1/20 0.36
NISCH Q9Y2I1 1/20 0.35
RBP4 P02753 2/20 0.35
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2570822 1.00 TDP1 (0.41) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL30008905 1.00 TDP1 (0.41) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL29405808 0.90 MAPT (0.44) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL380498 0.90 MAPT (0.44) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL28552345 0.89 TDP1 (0.40) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL29133656 0.86 TDP1 (0.35) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL9240035 0.86 TDP1 (0.35) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL9491543 0.82 TDP1 (0.43) TDP1ATMMAPTTP53ALDH1A1
SCHEMBL1160297 0.82 MEN1 (0.34) TDP1MAPTTP53ALDH1A1GAA
SCHEMBL9240542 0.82 APEX1 (0.38) TDP1MAPTALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577370-B2 Non-dust blend SI GROUP, INC. (US) 2026-03-17 US claimed
CN-115210311-B Dust free blends 瑞士新集团股份有限公司 2024-06-18 CN claimed
US-20210292649-A1 COMPOSITION SI GROUP, INC. 2021-09-23 US claimed
EP-3827047-A1 COMPOSITION SI Group Switzerland (CHAA) GmbH (CH) 2021-06-02 EP claimed
WO-2020021042-A1 COMPOSITION SI Group Switzerland (Chaa) Gmbh (CH) 2020-01-30 WO claimed
US-12577370-B2 Non-dust blend SI GROUP, INC. (US) 2026-03-17 US disclosed
CN-115210311-B Dust free blends 瑞士新集团股份有限公司 2024-06-18 CN disclosed
CN-115023467-B Thermoplastic polyester resin composition and molded article 东丽株式会社 2023-11-03 CN disclosed
US-20230090780-A1 Non-Dust Blend SI GROUP, INC. 2023-03-23 US disclosed
EP-4097174-A1 NON-DUST BLEND SI Group Switzerland (CHAA) GmbH (CH) 2022-12-07 EP disclosed
CN-115210311-A Dust-free blends 瑞士新集团股份有限公司 2022-10-18 CN disclosed
CN-115023467-A Thermoplastic polyester resin composition and molded article 东丽株式会社 2022-09-06 CN disclosed
US-20080146697-A1 Polyester molding for use with a casing SONY CORPORATION (JP) 2008-06-19 US disclosed
US-20070270527-A1 Resin Composition, Molded Product From Resin Composition and Method for Preparing Resin Composition Lerner, David, Littenberg, Krumholz & Mentlik, LLP 2007-11-22 US disclosed
US-20070257239-A1 Resin Composition, Molded Product Obtained From Resin Composition and Method for Preparation of Resin Composition SONY CORPORATION (JP) 2007-11-08 US disclosed
US-7285589-B2 Polyester molding for use with a casing SONY CORPORATION (JP) 2007-10-23 US disclosed
EP-1698658-A1 RESIN COMPOSITION, SHAPED ARTICLE USING SUCH RESIN COMPOSITION AND METHOD FOR PRODUCING RESIN COMPOSITION Sony Corporation (JP) 2006-09-06 EP disclosed
EP-1690899-A1 RESIN COMPOSITION, MOLDING THEREOF AND PROCESS FOR PRODUCING THE RESIN COMPOSITION Sony Corporation (JP) 2006-08-16 EP disclosed
US-20030018099-A1 Polyester molding for use with a casing Lerner, David, Littenberg, Krumholz & Mentlik, LLP 2003-01-23 US disclosed
EP-1275690-A2 Polyester molding for use with a casing SONY CORPORATION (JP) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292649-A1 COMPOSITION GPX4, TXN2, TXNRD2 TDP1 495/4885ATM 3115/4885MAPT 712/4885
US-12577370-B2 Non-dust blend NONO, POT1, PTPN11 TDP1 175/4885ATM 2829/4885MAPT 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.