Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801268 | 1.00 | ADRB3 (0.47) | ADRB3SLC16A3LMNAMEN1KMT2A | |
| Tetrabuthylammonium SCHEMBL6746933 | 0.90 | ADRB3 (0.40) | ADRB3SLC16A3LMNAMEN1KMT2A | |
| SCHEMBL5431193 | 0.82 | ADRB2 (0.45) | ADRB3LMNAADRB2ADRA1D | |
| SCHEMBL17660490 | 0.82 | KMT2A (0.39) | ADRB3MEN1KMT2AADRB2ADRA1D | |
| SCHEMBL5391885 | 0.82 | ADRB3 (0.45) | ADRB3ADRB2ADRA1D | |
| SCHEMBL5436285 | 0.82 | ADRB2 (0.42) | ADRB3LMNAADRB2ADRA1D | |
| SCHEMBL14357339 | 0.81 | ADRB2 (0.57) | ADRB3LMNAMEN1KMT2AADRB2 | |
| SCHEMBL14357338 | 0.81 | ADRB2 (0.57) | ADRB3LMNAMEN1KMT2AADRB2 | |
| SCHEMBL5423178 | 0.81 | ADRB2 (0.43) | ADRB3LMNAADRB2 | |
| SCHEMBL2829651 | 0.81 | ADRB2 (0.57) | ADRB3LMNAMEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097697-A1 | METHOD FOR SYNTHESIZING (1R)-1-(2,2-DIMETHYL-4H-1,3-BENZODIOXIN-6-YL)OXAZOLIDIN-2-ONE | 广东莱佛士制药技术有限公司 | 2023-06-08 | — | — | WO | disclosed |
| CN-1266126-C | Phenylethanolamine derivatives for the treatment of respiratory diseases | GLAXO GROUP LTD (GB) | 2006-07-26 | — | — | CN | disclosed |
| CN-1501911-A | Phenethanolamine derivatives for treatment of respiratory diseases | — | 2004-06-02 | — | — | CN | disclosed |