SCHEMBL25711237

SCHEMBL25711237

CC/C=C(\C=C(/C)C(C)(F)F)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936788 0.76 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL5936787 0.76 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL358241 0.74 GRIK1 (0.34) GRIK1GRIK2
SCHEMBL21728895 0.73
Acrylic Acid SCHEMBL10461112 0.68 LMNA (0.39) GRIK1GRIK2
SCHEMBL10631795 0.66
SCHEMBL1823090 0.66
SCHEMBL1446836 0.65
SCHEMBL4584137 0.65
Water SCHEMBL11376129 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023108108-A1 RAF KINASE INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS, LLC (US) 2023-06-15 WO disclosed