Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | POLD1 | P28340 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 17/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25718725 | 0.93 | P2RY2 (0.39) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL25712760 | 0.84 | TK1 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL24371748 | 0.81 | POLB (0.40) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL18844312 | 0.81 | POLB (0.40) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL13312464 | 0.80 | P2RY2 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL21414053 | 0.80 | P2RY2 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL14477331 | 0.80 | P2RY2 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL25572510 | 0.80 | P2RY2 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL14985191 | 0.80 | P2RY2 (0.41) | POLA1POLBPOLD1P2RY2P2RY4 | |
| SCHEMBL272716 | 0.78 | P2RY2 (0.39) | POLA1POLBPOLD1P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |