Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 7/20 | 0.81 |
| ▸ | BCL2 | P10415 | 9/20 | 0.62 |
| ▸ | BID | P55957 | 9/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 9/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24483399 | 0.92 | BCL2L1 (0.68) | BCL2L1BCL2BAK1 | |
| SCHEMBL25274600 | 0.90 | BCL2L1 (0.77) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL1567421 | 0.89 | BCL2L1 (1.00) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL24483918 | 0.89 | BCL2L1 (0.65) | BCL2L1BCL2 | |
| SCHEMBL25422653 | 0.87 | BCL2L1 (0.72) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL15539350 | 0.86 | BCL2L1 (0.80) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL25422864 | 0.86 | BCL2L1 (0.79) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL25422869 | 0.86 | BCL2L1 (0.79) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL30857697 | 0.85 | BCL2L1 (0.69) | BCL2L1BCL2BIDBCL2A1 | |
| SCHEMBL15539269 | 0.85 | BCL2L1 (0.77) | BCL2L1BCL2BIDBCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107606-A1 | BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-15 | — | — | WO | disclosed |