Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866038 | 0.77 | MAPK1 (0.35) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL1535991 | 0.74 | MAPK1 (0.34) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL12431439 | 0.74 | TSHR (0.38) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL1535989 | 0.74 | MAPK1 (0.34) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL16850495 | 0.72 | MAPK1 (0.33) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL9005349 | 0.72 | MAPK1 (0.33) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL16337476 | 0.70 | TSHR (0.36) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL16850497 | 0.69 | MAPK1 (0.34) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL13725734 | 0.69 | TSHR (0.38) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL5535228 | 0.69 | TSHR (0.38) | MAPK1NPC1TSHRRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |