SCHEMBL16337476

SCHEMBL16337476

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nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
NPC1 O15118 1/20 0.36
PTGS1 P23219 1/20 0.33
AKR1C3 P42330 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 2/20 0.32
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12431439 0.78 TSHR (0.38) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL561587 0.77 MAPT (0.39) PTGS1AKR1C3CYP2C9MAPTALDH1A1
SCHEMBL15563291 0.76 TSHR (0.37) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL15563292 0.76 TSHR (0.37) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL12572454 0.75 CYP2C9 (0.32) PTGS1AKR1C3CYP2C9MAPT
SCHEMBL2866038 0.75 MAPK1 (0.35) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL1535989 0.72 MAPK1 (0.34) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL1535991 0.72 MAPK1 (0.34) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL13725734 0.72 TSHR (0.38) TSHRNPC1MAPK1RAB9AHSD17B10
SCHEMBL13725736 0.72 TSHR (0.38) TSHRNPC1MAPK1RAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds L'OREAL (FR) 2021-09-28 US disclosed
US-9884004-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9884002-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9884003-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9814668-B2 Hair styling compositions comprising latex polymers L'OREAL (FR) 2017-11-14 US disclosed
US-9814669-B2 Hair cosmetic composition containing latex polymers and a silicone-organic polymer compound L'OREAL (FR) 2017-11-14 US disclosed
US-9795556-B2 Compositions and methods for treating hair L'OREAL (FR) 2017-10-24 US disclosed
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND L'OREAL (FR) 2016-06-23 US disclosed
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004115-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004118-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, NACA, DPM1 TSHR 3323/4885NPC1 4621/4885PTGS1 1285/4885
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND SUCLG1, NACA, EPM2A TSHR 2270/4885NPC1 3559/4885PTGS1 3413/4885
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds SRM, KRT18, ODC1 TSHR 4075/4885NPC1 4498/4885PTGS1 3993/4885
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, DPM1, NACA TSHR 4108/4885NPC1 4554/4885PTGS1 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.