Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314436 | 0.91 | CYP4F2 (0.41) | HSD11B1ALDH1A1POLBRAB9AHTT | |
| SCHEMBL6585961 | 0.84 | CYP2C19 (0.48) | CYP2C19ALDH1A1PPARGPPARASLC6A3 | |
| SCHEMBL11373445 | 0.84 | CYP2C19 (0.48) | CYP2C19ALDH1A1PPARGPPARASLC6A3 | |
| SCHEMBL29024354 | 0.84 | CYP2C19 (0.48) | CYP2C19ALDH1A1PPARGPPARASLC6A3 | |
| SCHEMBL22549674 | 0.83 | HSD11B1 (0.43) | HSD11B1ALDH1A1MMESLC6A3POLB | |
| SCHEMBL28840772 | 0.83 | MME (0.46) | CYP2C19ALDH1A1PPARGPPARAALOX5AP | |
| Hydrochloric Acid SCHEMBL5807511 | 0.82 | SLC6A2 (0.42) | HSD11B1SLC6A3CNR2 | |
| SCHEMBL5818358 | 0.82 | AKR1C1 (0.47) | CYP2C19ALDH1A1SLC6A3ADRB2RAB9A | |
| SCHEMBL22549561 | 0.81 | HSD11B1 (0.41) | HSD11B1ALDH1A1MMEPOLB | |
| SCHEMBL24663644 | 0.81 | HSD11B1 (0.41) | HSD11B1ALDH1A1MMEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685748-B2 | Spiro aromatic ring compound and application thereof | ETERN BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685748-B2 | Spiro aromatic ring compound and application thereof | PTPN1, PTPN11, PTPN5 | HSD11B1 257/4885CYP2C19 1114/4885ALDH1A1 1919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.