SCHEMBL2571390

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2571392	1.00	CNR2 (0.41)	CNR2CNR1HRH3TDP1P2RX7
	SCHEMBL9107658	0.83	NPC1 (0.44)	CNR2CNR1HRH3NPC1RAB9A
	SCHEMBL9110156	0.83	P2RX7 (0.43)	CNR2CNR1P2RX7ALDH1A1
	SCHEMBL9105776	0.83	P2RX7 (0.43)	CNR2CNR1P2RX7ALDH1A1
	SCHEMBL9107192	0.83	NPC1 (0.44)	CNR2CNR1HRH3NPC1RAB9A
	SCHEMBL9106063	0.83	CNR2 (0.58)	CNR2CNR1TDP1HDAC1HDAC8
	SCHEMBL9106074	0.83	CNR2 (0.58)	CNR2CNR1TDP1HDAC1HDAC8
	SCHEMBL2568867	0.81	HDAC1 (0.48)	CNR2CNR1HRH3GRM5HDAC1
	SCHEMBL2568865	0.81	HDAC1 (0.48)	CNR2CNR1HRH3GRM5HDAC1
	SCHEMBL9108258	0.80	IDH1 (0.43)	CNR2CNR1HRH3TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.