Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416927 | 0.71 | NOTUM (0.62) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL3035084 | 0.71 | NOTUM (0.46) | ALDH1A1GAAGFER | |
| SCHEMBL257553 | 0.71 | ROCK1 (0.60) | ROCK1ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL2538079 | 0.70 | MAPT (0.39) | ROCK1ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL12345961 | 0.69 | ROCK1 (0.49) | ROCK1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL22005465 | 0.68 | ROCK1 (0.51) | ROCK1ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL7075121 | 0.68 | ROCK1 (0.51) | ROCK1ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL6747225 | 0.68 | NOTUM (0.43) | ALDH1A1MAPTKMT2AHSD17B10LMNA | |
| SCHEMBL27612384 | 0.68 | LMNA (0.44) | ALDH1A1MAPTKMT2AHSD17B10THRB | |
| SCHEMBL12967741 | 0.68 | NOTUM (0.37) | ALDH1A1HTTMAPTKDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029763-A1 | DIAMINE, POLYIMIDE PRECURSOR, POLYIMIDE, LIQUID-CRYSTAL ALIGNMENT MATERIAL, LIQUID-CRYSTAL ALIGNMENT FILM, AND LIQUID-CRYSTAL DISPLAY ELEMENT | 日産化学工業株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |