Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.41 |
| ▸ | EGFR | P00533 | 7/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25718094 | 0.84 | BTK (0.41) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL25718091 | 0.81 | MAP2K7 (0.44) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL29002663 | 0.77 | MAP2K7 (0.43) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL31745489 | 0.75 | BTK (0.41) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL29002661 | 0.75 | BTK (0.42) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL29002681 | 0.75 | MAP2K7 (0.41) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL31745485 | 0.74 | BTK (0.42) | BTKEGFRMAP2K7KCNH2TGM2 | |
| SCHEMBL22676740 | 0.74 | BTK (0.49) | BTKEGFRMAP2K7KCNH2 | |
| SCHEMBL30303325 | 0.74 | BTK (0.49) | BTKEGFRMAP2K7KCNH2 | |
| SCHEMBL25715068 | 0.74 | BTK (0.41) | BTKEGFRMAP2K7KCNH2TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |