Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 12/20 | 0.41 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25716851 | 0.80 | BTK (0.42) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL30303904 | 0.75 | BTK (0.47) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL22676843 | 0.75 | BTK (0.47) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL31745444 | 0.75 | BTK (0.41) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL25715068 | 0.75 | BTK (0.41) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL25718094 | 0.75 | BTK (0.41) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL25715020 | 0.75 | FLT3 (0.43) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL22676078 | 0.75 | FGFR1 (0.51) | MAP2K7BTKEGFRKCNH2FLT3 | |
| SCHEMBL30303351 | 0.74 | BTK (0.46) | MAP2K7BTKTGM2EGFRKCNH2 | |
| SCHEMBL22676040 | 0.74 | BTK (0.46) | MAP2K7BTKTGM2EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |