Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | BTK | Q06187 | 10/20 | 0.41 |
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | CSF1R | P07333 | 5/20 | 0.41 |
| ▸ | KIT | P10721 | 5/20 | 0.41 |
| ▸ | FLT1 | P17948 | 5/20 | 0.41 |
| ▸ | FLT4 | P35916 | 5/20 | 0.41 |
| ▸ | LCK | P06239 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 4/20 | 0.40 |
| ▸ | BLK | P51451 | 4/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715018 | 0.83 | KDR (0.35) | FLT3KDRBTKCSF1RKIT | |
| SCHEMBL25715071 | 0.83 | BTK (0.49) | FLT3KDRBTKEGFRCSF1R | |
| SCHEMBL25718094 | 0.81 | BTK (0.41) | FLT3BTKEGFRKCNH2MAP2K7 | |
| SCHEMBL22676040 | 0.80 | BTK (0.46) | FLT3BTKEGFRKCNH2BLK | |
| SCHEMBL30303351 | 0.80 | BTK (0.46) | FLT3BTKEGFRKCNH2BLK | |
| SCHEMBL25716851 | 0.80 | BTK (0.42) | FLT3BTKEGFRKCNH2FGFR1 | |
| SCHEMBL25715068 | 0.79 | BTK (0.41) | FLT3KDRBTKEGFRKCNH2 | |
| SCHEMBL29002661 | 0.78 | BTK (0.42) | BTKEGFRKCNH2MAP2K7TGM2 | |
| SCHEMBL30303904 | 0.78 | BTK (0.47) | FLT3KDRBTKEGFRCSF1R | |
| SCHEMBL22676843 | 0.78 | BTK (0.47) | FLT3KDRBTKEGFRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |