Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.39 |
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715261 | 0.90 | EGFR (0.36) | BTKEGFRKCNH2MAP2K7ITK | |
| SCHEMBL25715286 | 0.89 | EGFR (0.34) | EGFRITKEPHB4FGFR4 | |
| SCHEMBL25718320 | 0.86 | GCK (0.37) | BTKEGFRKCNH2ITKEPHB4 | |
| SCHEMBL25718094 | 0.85 | BTK (0.41) | BTKEGFRKCNH2MAP2K7ERBB2 | |
| SCHEMBL25718327 | 0.85 | BTK (0.35) | BTKEGFRKCNH2MAP2K7ITK | |
| SCHEMBL25715151 | 0.82 | BTK (0.40) | BTKEGFRKCNH2MAP2K7EPHB4 | |
| SCHEMBL25718413 | 0.80 | ALOX5AP (0.41) | BTKEGFRITKFGFR4 | |
| SCHEMBL25715199 | 0.80 | BTK (0.33) | BTKEPHB4 | |
| SCHEMBL25718414 | 0.77 | ITK (0.36) | BTKEGFRKCNH2MAP2K7ITK | |
| SCHEMBL31745466 | 0.77 | BTK (0.36) | BTKEGFRKCNH2ITKGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |