Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.34 |
| ▸ | ITK | Q08881 | 4/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25718413 | 0.90 | ALOX5AP (0.41) | EGFRFGFR4ITKFGFR1CYP3A4 | |
| SCHEMBL25718196 | 0.89 | BTK (0.39) | EGFRFGFR4ITKEPHB4 | |
| SCHEMBL25715323 | 0.87 | GCK (0.34) | EGFRFGFR4ITKFGFR1CYP3A4 | |
| SCHEMBL25715301 | 0.83 | KDR (0.38) | EGFRFGFR4FGFR1CYP3A4CYP2D6 | |
| SCHEMBL25715261 | 0.80 | EGFR (0.36) | EGFRFGFR4ITKEPHB4 | |
| SCHEMBL25718320 | 0.77 | GCK (0.37) | EGFRITKABL1TEKEPHB4 | |
| SCHEMBL25715199 | 0.75 | BTK (0.33) | TEKEPHB4 | |
| SCHEMBL25718327 | 0.75 | BTK (0.35) | EGFRITKEPHB4 | |
| SCHEMBL25718094 | 0.74 | BTK (0.41) | EGFR | |
| SCHEMBL25716405 | 0.73 | CYP3A4 (0.45) | EGFRFGFR4FGFR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |