Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | CCNH | P51946 | 2/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | CDK14 | O94921 | 2/20 | 0.34 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25714798 | 0.88 | BTK (0.46) | BTKEGFR | |
| SCHEMBL25716990 | 0.84 | BTK (0.39) | BTKEGFR | |
| SCHEMBL30791524 | 0.84 | BTK (0.47) | BTKEGFR | |
| SCHEMBL25716989 | 0.83 | BTK (0.35) | BTKEGFR | |
| SCHEMBL25714796 | 0.82 | BTK (0.39) | BTKEGFR | |
| SCHEMBL31745494 | 0.80 | BTK (0.38) | BTKEGFRCCNKCCNA2CDK2 | |
| SCHEMBL30791511 | 0.78 | BTK (0.40) | BTKEGFR | |
| SCHEMBL25716987 | 0.75 | BTK (0.37) | BTKEGFR | |
| SCHEMBL30791515 | 0.74 | BTK (0.41) | BTK | |
| SCHEMBL25716848 | 0.74 | BTK (0.38) | BTKEGFRJAK3CDK14CCNY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |