Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.37 |
| ▸ | PIP4K2B | P78356 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 8/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CDK14 | O94921 | 2/20 | 0.35 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25718094 | 0.86 | BTK (0.41) | BTKEGFRERBB2 | |
| SCHEMBL25718199 | 0.81 | F10 (0.34) | BTKJAK3 | |
| SCHEMBL25718091 | 0.77 | MAP2K7 (0.44) | BTKEGFRBRD4 | |
| SCHEMBL31745494 | 0.76 | BTK (0.38) | BTKPIP4K2APIP4K2BEGFRJAK3 | |
| SCHEMBL25715529 | 0.75 | FLT3 (0.43) | BTKPIP4K2APIP4K2BEGFRJAK3 | |
| SCHEMBL25718318 | 0.74 | BTK (0.44) | BTKPIP4K2APIP4K2BEGFRJAK3 | |
| SCHEMBL25718089 | 0.73 | BTK (0.41) | BTKEGFR | |
| SCHEMBL25718196 | 0.73 | BTK (0.39) | BTKEGFRERBB2ITK | |
| SCHEMBL25716850 | 0.71 | BTK (0.41) | BTKEGFR | |
| SCHEMBL25715020 | 0.70 | FLT3 (0.43) | BTKEGFRJAK3ITKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |