Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477853 | 0.86 | LMNA (0.54) | LMNAHTTROCK2CYP3A4CYP2D6 | |
| SCHEMBL17088193 | 0.82 | KMT2A (0.67) | LMNAHTTKMT2AALDH1A1MAPT | |
| SCHEMBL25720255 | 0.82 | HPGD (0.49) | LMNAHTTKMT2AHPGDALDH1A1 | |
| SCHEMBL6282499 | 0.80 | GRM1 (0.46) | LMNACYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL25196861 | 0.79 | SMPD1 (0.62) | RAB9ACYP19A1 | |
| SCHEMBL30391457 | 0.79 | SMPD1 (0.62) | RAB9ACYP19A1 | |
| SCHEMBL11044058 | 0.79 | HPGD (0.56) | LMNAHTTKMT2AHPGDALDH1A1 | |
| SCHEMBL3073424 | 0.78 | NT5E (0.55) | LMNAKMT2AHPGDALDH1A1MAPT | |
| SCHEMBL1845879 | 0.78 | MAPT (0.49) | LMNACYP3A4CYP2D6CYP2C9KMT2A | |
| SCHEMBL7913254 | 0.77 | HPGD (0.55) | LMNAHTTKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |