Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23131444 | 0.92 | CSNK1D (0.69) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL23131442 | 0.89 | CSNK1D (0.65) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL4917536 | 0.88 | SMN1; SMN2 (0.81) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL28586215 | 0.80 | NPC1 (0.77) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL30443283 | 0.80 | NPC1 (0.77) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL23131724 | 0.79 | KDM4E (0.76) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4910853 | 0.79 | SMN1; SMN2 (0.80) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL2247099 | 0.79 | MAPT (1.00) | SMN1; SMN2MAPTTP53NPC1RAB9A | |
| SCHEMBL4910836 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 | |
| SCHEMBL4909759 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2MAPTTP53ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201339-A1 | USE OF THIAZOLE AMIDE COMPOUNDS FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201339-A1 | USE OF THIAZOLE AMIDE COMPOUNDS FOR MODULATING HUMAN IMMUNE RESPONSE | MYD88, IRF3, TLR1 | SMN1; SMN2 3657/4885MAPT 2310/4885TP53 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.