Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.36 |
| ▸ | HINT1 | P49773 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | NT5E | P21589 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715184 | 0.90 | SLC29A1 (0.34) | SLC29A1HINT1ADORA2AADORA2BADORA3 | |
| SCHEMBL25723791 | 0.87 | SLC29A1 (0.36) | SLC29A1HINT1ADORA2AADORA2BADORA3 | |
| SCHEMBL25723762 | 0.83 | HINT1 (0.46) | HINT1NT5E | |
| SCHEMBL25713475 | 0.78 | HINT1 (0.43) | SLC29A1HINT1ADORA2AADORA2BADORA3 | |
| SCHEMBL25720930 | 0.77 | CYP3A4 (0.41) | HINT1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL25713585 | 0.77 | CYP3A4 (0.41) | HINT1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL18512911 | 0.77 | CYP3A4 (0.41) | HINT1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL25723814 | 0.75 | HINT1 (0.42) | SLC29A1HINT1ADORA2AADORA2BADORA3 | |
| SCHEMBL23348935 | 0.75 | HINT1 (0.38) | SLC29A1HINT1ADORA2AADORA2BADORA3 | |
| SCHEMBL22474866 | 0.75 | HINT1 (0.38) | SLC29A1HINT1ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |