Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 8/20 | 0.58 |
| ▸ | IP6K3 | Q96PC2 | 4/20 | 0.58 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.58 |
| ▸ | PARP1 | P09874 | 9/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042406 | 0.88 | IP6K1 (0.61) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL7427860 | 0.79 | IP6K1 (0.68) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL8170598 | 0.78 | IP6K1 (0.71) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL22980875 | 0.77 | IP6K1 (0.66) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL9911097 | 0.77 | IP6K1 (0.66) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL25275583 | 0.77 | PARP1 (0.61) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL27947190 | 0.75 | IP6K1 (0.62) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL1360723 | 0.74 | PARP1 (0.77) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL496967 | 0.74 | IP6K1 (0.65) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL20334906 | 0.74 | IP6K1 (0.61) | IP6K1IP6K3IP6K2PARP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |