Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133253 | 0.84 | MAPK14 (0.40) | ATRLMNAPOLBCYP17A1BRD9 | |
| SCHEMBL30479160 | 0.80 | CYP17A1 (0.38) | ATRLMNAPOLBCYP17A1BRD9 | |
| SCHEMBL25723532 | 0.79 | ATR (0.39) | ATRCYP17A1BRD9IDO1GSK3B | |
| SCHEMBL6133366 | 0.72 | BRD9 (0.35) | LMNAPOLBBRD9IDO1GSK3B | |
| SCHEMBL6133365 | 0.72 | BRD9 (0.35) | LMNAPOLBBRD9IDO1GSK3B | |
| SCHEMBL2173526 | 0.71 | MAPK1 (0.41) | CYP17A1BRD9IDO1GSK3BDYRK1A | |
| SCHEMBL29260322 | 0.71 | ATR (0.41) | ATRCYP17A1BRD9IDO1NAMPT | |
| SCHEMBL29957527 | 0.70 | CYP17A1 (0.47) | ATRCYP17A1IDO1NAMPTMETAP1 | |
| SCHEMBL1197794 | 0.70 | CYP17A1 (0.47) | ATRCYP17A1IDO1NAMPTMETAP1 | |
| SCHEMBL27457955 | 0.70 | ATR (0.39) | ATRLMNACYP17A1BRD9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452982-A1 | SALTS AND SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES OF PREPARING THEREOF | Incyte Corporation (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-118660889-A | Salt and solid forms of FGFR inhibitors and methods of making the same | 因赛特公司 | 2024-09-17 | — | — | CN | disclosed |
| WO-2023122134-A1 | SALTS AND SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES OF PREPARING THEREOF | INCYTE CORPORATION (US) | 2023-06-29 | — | — | WO | disclosed |
| US-20230192722-A1 | SALTS AND SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES OF PREPARING THEREOF | INCYTE CORPORATION | 2023-06-22 | — | — | US | disclosed |
| US-20230192722-A1 | SALTS AND SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES OF PREPARING THEREOF | INCYTE CORPORATION | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192722-A1 | SALTS AND SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES OF PREPARING THEREOF | FGFR1, FGFR3, FGFR4 | ATR 1101/4885LMNA 4178/4885POLB 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.