Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20262326 | 0.81 | MAPK14 (0.35) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL20262324 | 0.81 | MAPK14 (0.35) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL20276702 | 0.81 | LMNA (0.47) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL20262443 | 0.79 | IRAK4 (0.41) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL31437491 | 0.79 | LMNA (0.40) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL22857998 | 0.78 | IRAK4 (0.45) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL27457665 | 0.77 | GSK3B (0.37) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL22857997 | 0.77 | CNR2 (0.53) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL27457954 | 0.77 | GSK3B (0.40) | ATRBRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL31555029 | 0.76 | IRAK4 (0.41) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |