Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARG | Q86W56 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724540 | 0.90 | PARG (0.49) | KDM4EALDH1A1KMT2APARGPLK1 | |
| SCHEMBL25423174 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL30478139 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL25724544 | 0.85 | PARG (0.46) | KDM4EALDH1A1KMT2APARGHDAC1 | |
| SCHEMBL25724546 | 0.84 | PARG (0.48) | KDM4EALDH1A1KMT2APARGPLK1 | |
| SCHEMBL25724418 | 0.84 | PARG (0.46) | KDM4EALDH1A1MEN1KMT2APARG | |
| SCHEMBL30478129 | 0.84 | PARG (0.43) | KDM4EALDH1A1MEN1KMT2APARG | |
| SCHEMBL25423746 | 0.84 | PARG (0.43) | KDM4EALDH1A1MEN1KMT2APARG | |
| SCHEMBL25724477 | 0.83 | PARG (0.59) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL30478132 | 0.83 | HDAC1 (0.44) | KDM4EALDH1A1MEN1KMT2APARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | disclosed |