SCHEMBL2572504

SCHEMBL2572504

COC1(C(=O)O)CCOCC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
FFAR3 O14843 1/20 0.35
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33
TSHR P16473 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RECQL P46063 1/20 0.32
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
MGLL Q99685 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24328374 0.86 FFAR3 (0.32) ALDH1A1FFAR3
SCHEMBL24328382 0.86 FFAR3 (0.32) ALDH1A1FFAR3
SCHEMBL1254874 0.86 FFAR3 (0.32) ALDH1A1FFAR3
SCHEMBL1468175 0.85
SCHEMBL29108746 0.82 FFAR3 (0.32) FFAR3CYP2C19NPSR1SMN1; SMN2LMNA
SCHEMBL12735418 0.81 SMN1; SMN2 (0.33) ALDH1A1CYP2C19CYP3A4CYP2C9PKM
SCHEMBL2300431 0.80 FFAR3 (0.38) FFAR3CYP2C19TSHRNPSR1CYP4F2
SCHEMBL5634851 0.80
SCHEMBL24780855 0.79 CYP3A4 (0.36) ALDH1A1CYP2C19CYP3A4CYP2C9PKM
SCHEMBL25841430 0.79 CYP3A4 (0.42) ALDH1A1CYP2C19CYP3A4CYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737453-A1 NOVEL SELENOPHENE DERIVATIVES Aigen Sciences Inc. (KR) 2026-05-06 EP disclosed
US-12516067-B2 Antagonists of the muscarinic acetylcholine receptor M4 VANDERBILT UNIVERSITY (US) 2026-01-06 US disclosed
EP-4615454-A1 SOS1 INHIBITORS Acerand Therapeutics (Hong Kong) Limited (HK) 2025-09-17 EP disclosed
US-20250145595-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 UNITED STATES GOVERNMENT 2025-05-08 US disclosed
US-20250034196-A1 ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) 2025-01-30 US disclosed
WO-2025005748-A1 NOVEL SELENOPHENE DERIVATIVES (주)아이젠사이언스 2025-01-02 WO disclosed
US-20240368150-A1 BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2024-11-07 US disclosed
EP-4430055-A1 ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF Suzhou Spring-Sea Bio-Pharmaceuticals Co., Ltd. (CN) 2024-09-18 EP disclosed
CN-118541365-A Antagonists of muscarinic acetylcholine receptor M4 范德堡大学 2024-08-23 CN disclosed
US-20240228468-A1 N-(6-((OCTAHYDROCYCLOPENTA[C]PYRROL-5-YI)AMINO)PYRIDAZIN-3-YL)PHENYL)CARBOXAMIDE AND (6- ((OCTAHYDROCYCLOPENTA[C]PYRROL-5-YL)AMINO)PYRIDAZIN-3-YL)BENZAMIDE DERIVATIVES AS MACHR M4 ANTAGONISTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS VANDERBILT UNIVERSITY 2024-07-11 US disclosed
US-20210300937-A1 Novel Labelled Cannabinergic Ligands and Related Analogs MAKRIYANNIS ALEXANDROS (US) 2021-09-30 US disclosed
WO-2021119265-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2021-06-17 WO disclosed
US-20120289502-A1 IMIDAZOLE DERIVATIVES KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-11-15 US disclosed
US-8273738-B2 Imidazole derivatives KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-09-25 US disclosed
EP-2090570-B1 IMIDAZOLE DERIVATIVE KYOWA HAKKO KIRIN CO LTD (JP) 2011-11-09 EP disclosed
US-20100152178-A1 IMIDAZOLE DERIVATIVES KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-06-17 US disclosed
EP-2090570-A1 IMIDAZOLE DERIVATIVE Kyowa Hakko Kirin Co., Ltd. (JP) 2009-08-19 EP disclosed
WO-2008093064-A1 L-ALANINE DERIVATIVES AS α5 BETA 1 ANTAGONISTS ASTRAZENECA AB (SE) 2008-08-07 WO disclosed
US-20080182842-A1 L-alanine derivatives as a5beta1 antagonists ASTRAZENECA AB (SE) 2008-07-31 US disclosed
US-20080182842-A1 L-alanine derivatives as a5beta1 antagonists ASTRAZENECA AB (SE) 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120289502-A1 IMIDAZOLE DERIVATIVES CNR1, CNR2, ARRB1 ALDH1A1 2997/4885FFAR3 148/4885CYP2C19 429/4885
US-20240228468-A1 N-(6-((OCTAHYDROCYCLOPENTA[C]PYRROL-5-YI)AMINO)PYRIDAZIN-3-YL)PHENYL)CARBOXAMIDE AND (6- ((OCTAHYDROCYCLOPENTA[C]PYRROL-5-YL)AMINO)PYRIDAZIN-3-YL)BENZAMIDE DERIVATIVES AS MACHR M4 ANTAGONISTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS CHRM5, CHRM1, CHRM2 ALDH1A1 1704/4885FFAR3 549/4885CYP2C19 1770/4885
US-20080182842-A1 L-alanine derivatives as a5beta1 antagonists ITGB1, ITGA2B, ITGB5 ALDH1A1 345/4885FFAR3 2164/4885CYP2C19 4749/4885
US-20240368150-A1 BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER BICRA, BRD4, CNR1 ALDH1A1 1572/4885FFAR3 438/4885CYP2C19 151/4885
US-20250034196-A1 ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF DCTD, NUDT1, TYMP ALDH1A1 3272/4885FFAR3 3856/4885CYP2C19 647/4885
US-20250145595-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 CHRM4, CHRM3, CHRM5 ALDH1A1 1885/4885FFAR3 247/4885CYP2C19 1671/4885
US-20100152178-A1 IMIDAZOLE DERIVATIVES CNR1, CNR2, ARRB1 ALDH1A1 2997/4885FFAR3 148/4885CYP2C19 429/4885
US-20210300937-A1 Novel Labelled Cannabinergic Ligands and Related Analogs CNR1, CNR2, CHRND ALDH1A1 3979/4885FFAR3 246/4885CYP2C19 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.