Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.42 |
| ▸ | MTOR | P42345 | 12/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25227992 | 0.86 | PIK3CA (0.48) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL25277713 | 0.85 | PIK3CA (0.45) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL30308905 | 0.82 | PIK3CA (0.45) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL25720157 | 0.82 | PIK3CA (0.45) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL30308860 | 0.80 | GPR119 (0.45) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL25720155 | 0.80 | GPR119 (0.45) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL25227750 | 0.79 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL25278157 | 0.78 | PIK3CA (0.43) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL30308875 | 0.77 | PIK3CA (0.41) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 | |
| SCHEMBL27271080 | 0.77 | PIK3CA (0.41) | PIK3CAPIK3CDPIK3CGMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107592-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |