SCHEMBL25726401

SCHEMBL25726401

CN(c1ccc2ncc(-c3ccc4[nH]ccc4c3)n2n1)C1CCOCC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FYN P06241 7/20 0.65
CCNT1 O60563 5/20 0.56
CDK9 P50750 5/20 0.56
CDK5 Q00535 5/20 0.56
CDK5R1 Q15078 5/20 0.56
DYRK3 O43781 4/20 0.56
DYRK1A Q13627 4/20 0.56
DYRK2 Q92630 4/20 0.56
DYRK1B Q9Y463 4/20 0.56
CCNA2 P20248 4/20 0.56
CDK2 P24941 4/20 0.56
ERN1 O75460 3/20 0.45
MTOR P42345 3/20 0.40
RIPK2 O43353 1/20 0.39
PIM1 P11309 2/20 0.39
ABL1 P00519 1/20 0.39
PGK1 P00558 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CSNK1E P49674 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932050 0.93 FYN (0.56) FYNCCNT1CDK9CDK5CDK5R1
SCHEMBL23932104 0.88 ERN1 (0.57) FYNCCNT1CDK9CDK5CDK5R1
SCHEMBL23932146 0.85 FYN (0.47) FYNCCNT1CDK9CDK5CDK5R1
SCHEMBL23931952 0.84 ERN1 (0.49) FYNCCNT1CDK9CDK5CDK5R1
SCHEMBL23931890 0.83 FYN (0.44) FYNDYRK1AERN1RIPK2PIM1
SCHEMBL23932231 0.81 FYN (0.42) FYNDYRK1AERN1RIPK2PIM1
SCHEMBL23931854 0.81 ERN1 (0.44) FYNCCNT1CDK9CDK5CDK5R1
SCHEMBL23931842 0.80 ERN1 (0.43) FYNERN1RIPK2PIM1
SCHEMBL25726406 0.80 FYN (0.68) FYNCCNT1CDK9CDK5CDK5R1
SCHEMBL23932159 0.80 FYN (0.47) FYNDYRK1APIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159542-A1 RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF THE UAB RESEARCH FOUNDATION (US) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159542-A1 RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF HNRNPR, HNRNPAB, RBM3 FYN 2657/4885CCNT1 4219/4885CDK9 3562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.