Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.52 |
| ▸ | CDK2 | P24941 | 4/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.52 |
| ▸ | CDK9 | P50750 | 4/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | PGK1 | P00558 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 3/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23931952 | 0.92 | ERN1 (0.49) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL25726401 | 0.88 | FYN (0.65) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL23931854 | 0.87 | ERN1 (0.44) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL23932050 | 0.85 | FYN (0.56) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL23932146 | 0.84 | FYN (0.47) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL23931890 | 0.84 | FYN (0.44) | ERN1PIM1FYNDYRK1ARIPK2 | |
| SCHEMBL23931842 | 0.83 | ERN1 (0.43) | ERN1PIM1FYNRIPK2 | |
| SCHEMBL23931850 | 0.82 | ALDH1A1 (0.46) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL25726433 | 0.82 | DYRK1A (0.56) | ERN1CDK5CDK2CCNT1CDK9 | |
| SCHEMBL23932231 | 0.82 | FYN (0.42) | ERN1PIM1FYNDYRK1ARIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435091-B2 | RNA-binding protein multimerization inhibitors and methods of use thereof | THE UAB RESEARCH FOUNDATION (US) | 2025-10-07 | — | — | US | disclosed |
| US-20230159542-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159542-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159542-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2021216757-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021216757-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159542-A1 | RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF | HNRNPR, HNRNPAB, RBM3 | ERN1 517/4885CDK5 2409/4885CDK2 2845/4885 |
| US-12435091-B2 | RNA-binding protein multimerization inhibitors and methods of use thereof | HNRNPR, HNRNPAB, RBM3 | ERN1 517/4885CDK5 2409/4885CDK2 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.