SCHEMBL2573166

SCHEMBL2573166

O=C(O)c1ccc([S+]([O-])c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.60
TP53 P04637 1/20 0.60
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
SRD5A2 P31213 4/20 0.52
CA12 O43570 2/20 0.50
CA3 P07451 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
ALDH1A1 P00352 2/20 0.48
ALOX15 P16050 1/20 0.48
TPMT P51580 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9134580 0.98 TSHR (0.57) TSHRTP53CA1CA2SRD5A2
SCHEMBL9132801 0.98 TSHR (0.57) TSHRTP53CA1CA2SRD5A2
SCHEMBL9133716 0.98 TSHR (0.57) TSHRTP53CA1CA2SRD5A2
SCHEMBL9132486 0.98 TSHR (0.57) TSHRTP53CA1CA2SRD5A2
SCHEMBL506129 0.93 TSHR (0.54) TSHRTP53CA1CA2SRD5A2
Tetramethylammonium Ion SCHEMBL9133781 0.91 TSHR (0.50) TSHRTP53CA1CA2SRD5A2
Tetramethylammonium Ion SCHEMBL9137931 0.91 TSHR (0.50) TSHRTP53CA1CA2SRD5A2
Guanidine SCHEMBL9464570 0.89 TSHR (0.48) TSHRTP53CA1CA2SRD5A2
Guanidine SCHEMBL9460190 0.89 TSHR (0.48) TSHRTP53CA1CA2SRD5A2
SCHEMBL10966816 0.88 PARP10 (0.58) TSHRTP53CA1CA2SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP claimed
US-5756634-A Liquid one component PU stoving enamels HUELS AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
EP-3747934-B1 POLYARYLENE SULFIDE COPOLYMER AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2024-04-24 EP disclosed
CN-115010921-B High molecular weight semi-aromatic polyamide with narrow molecular weight distribution and continuous preparation method thereof 浙江新和成特种材料有限公司 2023-07-18 CN disclosed
US-20230220162-A1 POLYARYLENE SULFIDE PRODUCTION METHOD, POLYARYLENE SULFIDE COPOLYMER PRODUCTION METHOD, AND POLYARYLENE SULFIDE TORAY INDUSTRIES, INC. (JP) 2023-07-13 US disclosed
EP-4206259-A1 POLYARYLENE SULFIDE PRODUCTION METHOD, POLYARYLENE SULFIDE COPOLYMER PRODUCTION METHOD, AND POLYARYLENE SULFIDE Toray Industries, Inc. (JP) 2023-07-05 EP disclosed
US-11440997-B2 Polyarylene sulfide copolymer and method of producing the same TORAY INDUSTRIES, INC. (JP) 2022-09-13 US disclosed
CN-115010921-A High molecular weight semi-aromatic polyamide with narrow molecular weight distribution and continuous preparation method thereof 浙江新和成特种材料有限公司 2022-09-06 CN disclosed
US-20220267542-A1 FIBER-REINFORCED POLYARYLENE SULFIDE COPOLYMER COMPOSITE SUBSTRATE, METHOD OF MANUFACTURING SAME, AND MOLDED ARTICLE INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2022-08-25 US disclosed
EP-4006086-A1 FIBER-REINFORCED POLYARYLENE SULFIDE COPOLYMER COMPOSITE SUBSTRATE, METHOD FOR MANUFACTURING SAME, AND MOLDED ARTICLE INCLUDING SAME Toray Industries, Inc. (JP) 2022-06-01 EP disclosed
WO-2022045105-A1 POLYARYLENE SULFIDE PRODUCTION METHOD, POLYARYLENE SULFIDE COPOLYMER PRODUCTION METHOD, AND POLYARYLENE SULFIDE 東レ株式会社 2022-03-03 WO disclosed
US-4175178-A NONFLAMMABLE FILMS AND FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4175180-A FILMS OR FILAMENTS, NONFLAMMABLE S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4175174-A FILMS OR FILAMENTS, NONFLAMMABLE S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4172935-A FILMS, FILAMENTS S.A TEXACO BELGIUM N.V. (BE) 1979-10-30 US disclosed
US-4165424-A FILMS, FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1979-08-21 US disclosed
US-4151152-A POLYESTERURETHANES, SHELF LIFE VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
EP-0001468-A1 Powdered coating products, process for their preparation and their use CHEMISCHE WERKE HÜLS AG (DE) 1979-04-18 EP disclosed
EP-0001467-A1 Stoving lacquers having an extended pot life on the basis of polyisocyanate masked with imidazolines CHEMISCHE WERKE HÜLS AG (DE) 1979-04-18 EP disclosed
US-4098768-A FILMS, FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1978-07-04 US disclosed