Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573166 | 0.98 | TSHR (0.60) | TSHRTP53CA1CA2SRD5A2 | |
| SCHEMBL9132801 | 0.95 | TSHR (0.57) | TSHRTP53CA1CA2SRD5A2 | |
| SCHEMBL9133716 | 0.95 | TSHR (0.57) | TSHRTP53CA1CA2SRD5A2 | |
| SCHEMBL9132486 | 0.95 | TSHR (0.57) | TSHRTP53CA1CA2SRD5A2 | |
| SCHEMBL506129 | 0.91 | TSHR (0.54) | TSHRTP53CA1CA2SRD5A2 | |
| Tetramethylammonium Ion SCHEMBL9133781 | 0.89 | TSHR (0.50) | TSHRTP53CA1CA2SRD5A2 | |
| Tetramethylammonium Ion SCHEMBL9137931 | 0.89 | TSHR (0.50) | TSHRTP53CA1CA2SRD5A2 | |
| Guanidine SCHEMBL9464570 | 0.87 | TSHR (0.48) | TSHRTP53CA1CA2SRD5A2 | |
| Guanidine SCHEMBL9460190 | 0.87 | TSHR (0.48) | TSHRTP53CA1CA2SRD5A2 | |
| SCHEMBL10966816 | 0.86 | PARP10 (0.58) | TSHRTP53CA1CA2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378571-A | Toners for electrography | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| US-5274184-A | Aryl sulphide, aryl sulphoxide and aryl sulphone compounds | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |