Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.43 |
| ▸ | CNR1 | P21554 | 9/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31730946 | 1.00 | CNR2 (0.43) | CNR2CNR1PDE10AHDAC1ALDH1A1 | |
| SCHEMBL25733242 | 0.85 | CNR2 (0.38) | CNR2CNR1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL31731048 | 0.85 | CNR2 (0.38) | CNR2CNR1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL31730929 | 0.83 | CNR2 (0.46) | CNR2CNR1PDE10AHDAC1ALDH1A1 | |
| SCHEMBL25733267 | 0.83 | CNR2 (0.46) | CNR2CNR1PDE10AHDAC1ALDH1A1 | |
| SCHEMBL25281801 | 0.82 | LMNA (0.48) | CNR2CNR1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL31730882 | 0.82 | PIK3CA (0.41) | CNR2CNR1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL25732836 | 0.82 | PIK3CA (0.41) | CNR2CNR1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL31730971 | 0.82 | CNR2 (0.43) | CNR2CNR1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL25732832 | 0.82 | CNR2 (0.43) | CNR2CNR1PDE10AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |