SCHEMBL25733686

SCHEMBL25733686

CC1N(c2ccccc2)c2nccnc2N1c1cccc2c1oc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.37
▸ HSD17B10 Q99714 5/20 0.37
▸ MEN1 O00255 5/20 0.37
▸ KMT2A Q03164 5/20 0.37
▸ MAPT P10636 4/20 0.37
▸ HTT P42858 3/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ HCRTR1 O43613 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ DRD4 P21917 1/20 0.36
▸ CYP2C19 P33261 1/20 0.35
▸ LMNA P02545 3/20 0.34
▸ NPC1 O15118 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ NPY1R P25929 1/20 0.33
▸ NPY2R P49146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25705652 0.92 TSHR (0.36) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL27432157 0.90 ALDH1A1 (0.40) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL26369900 0.87 PIK3CA (0.34) KDM4EALDH1A1
SCHEMBL24851113 0.84 MEN1 (0.39) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL25721333 0.83 DRD4 (0.34) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL26776946 0.83 DRD4 (0.34) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL19224781 0.82 TSHR (0.35) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL19258090 0.82 TSHR (0.35) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL19258253 0.82 TSHR (0.35) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL25778842 0.82 ALDH1A1 (0.30) HSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 — — US disclosed
US-11690285-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR TSHR 168/4885HSD17B10 4353/4885MEN1 3677/4885
US-11690285-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND TSHR 4120/4885HSD17B10 2970/4885MEN1 3990/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR TSHR 168/4885HSD17B10 4353/4885MEN1 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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