SCHEMBL25733944

SCHEMBL25733944

CC1COCCN1C(=O)CN(C)S(=O)(=O)c1ccc(N2CCCC2)c(-c2cc3ccc(CCc4ccc5cc(-c6cc(S(=O)(=O)N(C)CC(=O)N7CC8CC7CO8)ccc6N6CCCC6)[nH]c5c4)cc3[nH]2)c1

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
STT3A P46977 1/20 0.73
STT3B Q8TCJ2 1/20 0.73
RORC P51449 2/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25726277 0.86 STT3A (0.72) STT3ASTT3BKMT2A
SCHEMBL25726233 0.86 STT3A (0.72) STT3ASTT3BKMT2A
SCHEMBL25726112 0.85 STT3A (1.00) STT3ASTT3BKMT2A
SCHEMBL25726108 0.85 STT3A (1.00) STT3ASTT3BKMT2A
SCHEMBL25725788 0.85 STT3A (1.00) STT3ASTT3BKMT2A
SCHEMBL25733879 0.78 STT3A (0.85) STT3ASTT3BRORCKMT2A
SCHEMBL25726328 0.78 STT3A (0.85) STT3ASTT3BRORCKMT2A
SCHEMBL25726324 0.76 STT3A (0.82) STT3ASTT3BKMT2A
SCHEMBL25726322 0.76 STT3A (0.82) STT3ASTT3BKMT2A
SCHEMBL25725970 0.73 STT3A (0.78) STT3ASTT3BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114428-A1 HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE Vir Biotechnology, Inc. (US) 2023-06-22 WO disclosed