Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MPL | P40238 | 2/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779428 | 0.92 | KIF11 (0.68) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9779088 | 0.90 | KIF11 (0.66) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL12240628 | 0.86 | KIF11 (0.74) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL29402876 | 0.82 | KIF11 (0.69) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL20659826 | 0.82 | KIF11 (0.69) | KIF11KDM4EALDH1A1HPGDHTT | |
| Toluene SCHEMBL7897249 | 0.81 | KIF11 (0.79) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL21692093 | 0.81 | KIF11 (0.68) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL20247764 | 0.81 | KIF11 (0.56) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL15002835 | 0.80 | KIF11 (0.60) | KIF11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL22652998 | 0.79 | KIF11 (0.82) | KIF11KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649249-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649249-B2 | Compounds for electronic devices | DDT, CYP2C9, CYP2D6 | KIF11 3038/4885KDM4E 2128/4885ALDH1A1 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.