Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447299 | 0.86 | MEN1 (0.44) | MAPTXBP1NPSR1TDP1MEN1 | |
| SCHEMBL30776077 | 0.81 | POLB (0.49) | MAPTXBP1NPSR1TDP1MEN1 | |
| SCHEMBL23447220 | 0.81 | ACE (0.49) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL23447293 | 0.81 | MEN1 (0.48) | MAPTXBP1NPSR1TDP1MEN1 | |
| SCHEMBL28931267 | 0.79 | KMT2A (0.50) | MAPTXBP1NPSR1TDP1MEN1 | |
| SCHEMBL28931266 | 0.79 | KMT2A (0.50) | MAPTXBP1NPSR1TDP1MEN1 | |
| SCHEMBL14450593 | 0.77 | MEN1 (0.48) | MAPTXBP1NPSR1TDP1MEN1 | |
| SCHEMBL19564830 | 0.77 | MEN1 (0.45) | MEN1ALDH1A1HPGDKMT2ALTA4H | |
| SCHEMBL12145038 | 0.77 | MEN1 (0.45) | MEN1ALDH1A1HPGDKMT2ALTA4H | |
| SCHEMBL24945920 | 0.76 | ACE (0.55) | ACEKLK7KLK5SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190360-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG SYNERGIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | Chongqing Upgra Biotechnology Co., Ltd. (CN) | 2023-06-07 | — | — | EP | disclosed |