Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447293 | 0.95 | MEN1 (0.48) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL24235721 | 0.88 | LTA4H (0.47) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL23463314 | 0.88 | ACE (0.52) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL22300308 | 0.88 | ACE (0.52) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL23447220 | 0.88 | ACE (0.49) | MEN1ALDH1A1HPGDKMT2AACE | |
| SCHEMBL24235765 | 0.86 | CTSS (0.44) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL25735511 | 0.86 | MAPT (0.39) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL30776077 | 0.84 | POLB (0.49) | MEN1ALDH1A1HPGDKMT2AACE | |
| SCHEMBL24235725 | 0.84 | MEN1 (0.49) | MEN1ALDH1A1HPGDKMT2APSMB5 | |
| SCHEMBL24235567 | 0.84 | LTA4H (0.49) | MEN1ALDH1A1HPGDKMT2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |