Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 13/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711157 | 1.00 | OPRL1 (1.00) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL1711153 | 1.00 | OPRL1 (1.00) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL29408438 | 1.00 | OPRL1 (1.00) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL30456124 | 0.98 | OPRL1 (0.96) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL22408650 | 0.98 | OPRL1 (0.96) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL22408651 | 0.98 | OPRL1 (0.96) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL1710960 | 0.96 | OPRL1 (0.93) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL1710965 | 0.96 | OPRL1 (0.93) | OPRL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL3592330 | 0.89 | OPRL1 (0.79) | OPRL1OPRM1OPRD1KCNH2 | |
| SCHEMBL2238943 | 0.89 | OPRL1 (0.79) | OPRL1OPRM1OPRD1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | OPRL1 2460/4885OPRM1 2668/4885OPRD1 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.