Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | USP25 | Q9UHP3 | 3/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649852 | 0.84 | AR (0.45) | HDAC1PARP1PARP6PARP2PARP3 | |
| SCHEMBL25916779 | 0.84 | AR (0.45) | HDAC1PARP1PARP6PARP2PARP3 | |
| SCHEMBL24649917 | 0.84 | AR (0.45) | HDAC1PARP1PARP6PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL29202601 | 0.83 | AR (0.44) | HDAC1PARP1PARP6PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL29202657 | 0.83 | AR (0.44) | HDAC1PARP1PARP6PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL29202603 | 0.83 | AR (0.44) | HDAC1PARP1PARP6PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL30888875 | 0.83 | AR (0.44) | HDAC1PARP1PARP6PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL30888884 | 0.83 | AR (0.44) | HDAC1PARP1PARP6PARP2PARP3 | |
| SCHEMBL30385503 | 0.81 | CHRNB2 (0.55) | HRH3HDAC1PARP1TNKSPARP6 | |
| SCHEMBL4933955 | 0.81 | CHRNB2 (0.55) | HRH3HDAC1PARP1TNKSPARP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |