Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | DDO | Q99489 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14694268 | 0.81 | GAA (0.47) | DAODDONSD2ARNPY5R | |
| SCHEMBL13186438 | 0.74 | DAO (0.46) | DAODDONSD2HRH4KDM4E | |
| SCHEMBL694774 | 0.73 | MGAM (0.45) | DAODDONSD2NPY5RMGAM | |
| SCHEMBL11488176 | 0.72 | DAO (0.55) | DAODDONSD2HRH4KDM4E | |
| SCHEMBL16105092 | 0.72 | DAO (0.50) | DAODDONSD2HRH4KDM4E | |
| SCHEMBL4884445 | 0.70 | DHODH (0.55) | DAODDONSD2KDM4EALDH1A1 | |
| SCHEMBL16382926 | 0.70 | KDM4E (0.56) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL11657032 | 0.70 | CYP1A1 (0.49) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1132837 | 0.69 | ACHE (0.41) | — | |
| SCHEMBL16382909 | 0.68 | DAO (0.46) | DAODDONSD2HRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |