Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25740902 | 1.00 | KMT2A (0.33) | KMT2ANOS1GAAMAPTHRH3 | |
| SCHEMBL15499052 | 0.90 | NOS1 (0.34) | KMT2ANOS1GAAMAPTNOS3 | |
| SCHEMBL25741022 | 0.87 | KMT2A (0.34) | KMT2ANOS1GAAMAPTHRH3 | |
| SCHEMBL6155217 | 0.84 | CYP2B6 (0.40) | KMT2ANOS1GAAMAPTHRH3 | |
| SCHEMBL25741934 | 0.82 | NOS1 (0.33) | KMT2ANOS1GAAMAPTHRH3 | |
| SCHEMBL14857835 | 0.81 | CYP2B6 (0.44) | KMT2ANOS1CYP2B6 | |
| SCHEMBL25741450 | 0.81 | NOS1 (0.36) | KMT2ANOS1GAAMAPTHRH3 | |
| SCHEMBL15499053 | 0.80 | NOS1 (0.36) | KMT2ANOS1 | |
| SCHEMBL1418289 | 0.79 | CYP2B6 (0.47) | KMT2ANOS1CYP2B6 | |
| SCHEMBL5141170 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |