Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573789 | 0.93 | LRRK2 (0.68) | LRRK2SGMS2CYP11B1CYP11B2SMPD1 | |
| SCHEMBL1318330 | 0.88 | LRRK2 (0.52) | LRRK2SGMS2CYP11B1CYP11B2MET | |
| SCHEMBL1315386 | 0.87 | MCL1 (0.60) | LRRK2SGMS2CYP11B1CYP11B2SMPD1 | |
| SCHEMBL12121482 | 0.87 | MKNK1 (0.53) | HDAC1MKNK1MKNK2 | |
| SCHEMBL20291171 | 0.87 | SGMS2 (0.74) | LRRK2SGMS2MET | |
| SCHEMBL20291299 | 0.86 | LRRK2 (0.68) | LRRK2SGMS2CYP11B1CYP11B2MET | |
| SCHEMBL2574796 | 0.84 | LRRK2 (0.68) | LRRK2MKNK2 | |
| SCHEMBL1316038 | 0.82 | LRRK2 (0.61) | LRRK2SGMS2CYP11B1CYP11B2HDAC1 | |
| SCHEMBL20290837 | 0.82 | LRRK2 (0.85) | LRRK2SGMS2MET | |
| SCHEMBL12121601 | 0.82 | LRRK2 (0.51) | LRRK2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |