Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11303192 | 1.00 | CYP1A2 (0.43) | CYP1A2NPSR1MAPTMEN1KMT2A | |
| SCHEMBL14218899 | 0.89 | DPP4 (0.35) | CYP1A2NPSR1MAPTMEN1KMT2A | |
| SCHEMBL11919623 | 0.89 | DPP4 (0.35) | CYP1A2NPSR1MAPTMEN1KMT2A | |
| SCHEMBL11080010 | 0.81 | NPSR1 (0.36) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11302329 | 0.81 | CYP1A2 (0.44) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16790659 | 0.80 | SMN1; SMN2 (0.46) | NPSR1MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL18629006 | 0.80 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22838077 | 0.80 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL812782 | 0.80 | CYP1A2 (0.42) | CYP1A2NPSR1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5418297 | 0.80 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |