Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | CD44 | P16070 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Tolylamine SCHEMBL23093681 | 0.83 | CYP3A4 (0.83) | CYP3A4TDP1CD44TSHRSMN1; SMN2 | |
| O-Xylene SCHEMBL28544206 | 0.83 | TSHR (0.59) | CYP3A4TDP1TSHRACHEALDH1A1 | |
| O-Xylene SCHEMBL28877080 | 0.83 | TSHR (0.59) | CYP3A4TDP1TSHRACHEALDH1A1 | |
| O-Tolylamine SCHEMBL29441724 | 0.83 | — | — | |
| O-Tolylamine SCHEMBL31145800 | 0.83 | — | — | |
| O-Tolylamine SCHEMBL8469060 | 0.83 | CYP3A4 (0.94) | CYP3A4TDP1CD44TSHRSMN1; SMN2 | |
| O-Tolylamine SCHEMBL9613766 | 0.83 | CYP3A4 (0.94) | CYP3A4TDP1CD44TSHRSMN1; SMN2 | |
| O-Tolylamine SCHEMBL15789 | 0.83 | — | — | |
| O-Xylene SCHEMBL29026505 | 0.80 | TSHR (0.56) | CYP3A4TDP1TSHRACHEALDH1A1 | |
| O-Tolylamine SCHEMBL17456823 | 0.80 | CYP3A4 (0.88) | CYP3A4TDP1CD44TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466946-B1 | FLAME-RETARDANT RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7205346-B2 | halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants | POLYPLASTICS CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| US-20040254270-A1 | Flame-retardant resin composition | POLYPLASTICS CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1466946-A1 | FLAME-RETARDANT RESIN COMPOSITION | Polyplastics Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |