Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742553 | 0.85 | FUCA1 (0.60) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL20745525 | 0.81 | FUCA1 (0.49) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL25740973 | 0.81 | HRH3 (0.57) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL16764857 | 0.81 | FUCA1 (0.49) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL23159839 | 0.81 | FUCA1 (0.57) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL23162411 | 0.81 | FUCA1 (0.57) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL16764982 | 0.81 | FUCA1 (0.49) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL16525718 | 0.81 | HRH3 (0.57) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL21483083 | 0.81 | HRH3 (0.57) | FUCA1SIGMAR1S1PR1S1PR5GBA1 | |
| SCHEMBL20858838 | 0.79 | FUCA1 (0.53) | FUCA1SIGMAR1S1PR1S1PR5GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |