Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16525718 | 1.00 | HRH3 (0.57) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL17266469 | 0.88 | HRH3 (0.72) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL4094332 | 0.88 | HRH3 (0.72) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL4094335 | 0.88 | HRH3 (0.72) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL12050627 | 0.88 | HRH3 (0.72) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL4094330 | 0.88 | HRH3 (0.72) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL12205371 | 0.84 | ACHE (0.66) | HRH3HRH4ACHEFUCA1SIGMAR1 | |
| SCHEMBL14742553 | 0.84 | FUCA1 (0.60) | ACHEFUCA1SIGMAR1MC4RS1PR1 | |
| SCHEMBL25741981 | 0.81 | FUCA1 (0.50) | ACHEFUCA1SIGMAR1S1PR1S1PR5 | |
| SCHEMBL13291911 | 0.81 | ACHE (0.58) | HRH3HRH4ACHEFUCA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197842-A1 | BCL6 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-10-17 | — | — | WO | disclosed |