⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309930 | 1.00 | — | — | |
| SCHEMBL19122720 | 1.00 | — | — | |
| SCHEMBL12414623 | 1.00 | — | — | |
| SCHEMBL804927 | 1.00 | — | — | |
| SCHEMBL14626990 | 1.00 | — | — | |
| SCHEMBL12990432 | 0.84 | FUCA1 (0.36) | — | |
| SCHEMBL26452946 | 0.82 | GBA1 (0.44) | — | |
| SCHEMBL788564 | 0.82 | GBA1 (0.44) | — | |
| SCHEMBL21846672 | 0.80 | TRPA1 (0.34) | — | |
| SCHEMBL13713505 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357254-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-09 | — | — | US | disclosed |
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-18 | — | — | US | disclosed |
| US-11691979-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-04 | — | — | US | disclosed |